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Recombinant Human ILDR2 ECD-Mouse IgG2b Fc


Catalog Number Product Size Price
P0851-100 Recombinant Human ILDR2 ECD-Mouse IgG2b Fc 100 µg $2400 Order
P0851-B Recombinant Human ILDR2 ECD-Mouse IgG2b Fc Bulk Inquire

Product Specifications


Source: Human ILDR2 (Accession # XP_016856747.1) extracellular domain (Leu36-Glu201) fused with mouse IgG2b Fc produced from HEK293 cells.
Structure: Disulfide-linked homodimer
Predicted N-terminal: Leu 36
Predicted Molecular Weight: 91 kDa (dimer)
Apparent Molecular Weight on SDS-PAGE: 50.0 kDa, reducing conditions
Formulation: 0.22 µm filtered protein solution in PBS
Storage: < -20°C 
Estimated Purity: >95% as determined by SDS-PAGE
Protein Endotoxin Level: Not measured
Protein Aggregation: No obvious protein aggregates detected by SEC analysis

Product Description


Application: Biochemical analysis
Product Description: ILDR2 (immunoglobulin-like domain-containing receptor 2) has four major isoforms. It is a single-pass type I transmembrane protein containing an amino terminal immunoglobulin-like domain (IgV like) and a long, carboxy tail (1). It was found to localize in the endoplasmic reticulum and is suggested to be involved in lipid homeostasis and ER stress pathways (2). It has also been associated with type 2 diabetes (1). It belongs to immunoglobulin superfamily and LISCH7 family (3).
Other Names: C1orf32, “Lisch-like”
References:
  1. Dokmanovic-Chouinard, M. et al. (2008) PLoS Genet. 4(7).
  2. Watanabe, K. et al. (2013) PLoS ONE. 8(6).
  3. Tomohihto, H. et al. (2013) J. Cell. Sci. 126:966.
Product Datasheet: Download PDF

Data


SDS-PAGE Analysis

10 µg/lane of human ILDR2 ECD-mouse IgG2b Fc was resolved on SDS-PAGE gel in non-reducing (NR) and reducing (R) conditions and visualized by coomassie blue staining

Size Exclusion Chromatography (SEC) Analysis