CynoHER2-CT26 Stable Cell Line

Catalog Number Product Size Price
C3041 CynoHER2-CT26 Stable Cell Line 2 vials $2000 Order

Product Specifications

Catalog Number C3041
Cell Line Name CT26 stable cell line expressing receptor protein tyrosine kinase erbB-2 (HER2) from cynomolgus monkey (CynoHER2-CT26)
Accession Number XP_005584091.2
Host Cell CT26, mouse colon carcinoma cells
Quantity Two vials of frozen cells (2x106 per vial)
Culture Medium RPMI with 10% FBS, 20 µg/ml puromycin
Freezing Medium 90% FBS and 10% DMSO
Storage Liquid nitrogen upon receipt
Product Datasheet: Download PDF

Representative Data

Detection of CynoHER2 expression on CynoHER2-CT26 stable cells using Trastuzumab, an anti-human HER2 monoclonal antibody which cross-react with cynoHER2. (Cat.#A1019).


Her-2, also called Neu and ErbB2 (human epidermal growth factor receptor 2), is a type I membrane protein that is a member of the ErbB family of receptor tyrosine kinases. ErbB family members include EGFR, ErbB2 (Neu, Her-2), ErbB3 (Her-3), and ErbB4 (Her-4) and they serve as receptors for the epidermal growth factor (EGF) family of growth factors. Her-2 is widely expressed in epithelial cells and is over-expressed on a large population of breast cancer cells. Comparing to the other members of the ErbB family, Her-2 is unique in that it has no known ligands and it can heterodimerize with the other members of the ErbB family to form higher affinity signaling complexes. Mature human Her-2 consists of 1233 amino acids (aa) with a 630 aa extracellular domain, a 23 aa transmembrane region, and a 580 aa cytoplasmic domain. Her-2 may play a variety of roles in development and regulation of cell growth and differentiation (1-6).


Ullrich, A. et al. (1984) Nature. 309:418.
Graus-Porta, D. et al. (1997) EMBO J. 16:1647.
Singh, A.B. and R.C. Harris (2005) Cell. Signal. 17:1183.
Burgess, A.W. et al. (2003) Mol. Cell. 12:541.
Roskoski Jr., R. (2004) Biochem. Biophys. Res. Commun. 319:1.
Lemmon, M.A. et al. (1997) EMBO J. 16:281.