Human FOLR1-CHO-K1 Stable Cell Line

Catalog Number Product Size Price
C3038 Human FOLR1-CHO-K1 Stable Cell Line 2 vials $2000 Order

Background Information

Folate receptor 1 (Folate receptor alpha, FOLR1) is a glycosyl-phosphatidylinositol (GPI)-linked membrane-bound protein, which exhibits a high affinity for folic acid and its reduced folic acid derivatives. FOLR1 mediates delivery of 5-methyltetrahydrofolate to the interior of cells. FOLR1 is involved in several cellular processes, including cell growth, survival, and signaling pathways. FOLR1 is expressed in kidney, placenta, serum, milk, and in several cell lines, while its expression has been found to be elevated in tumors of epithelial origin compared to normal tissue, including ovarian, breast, brain, lung and colorectal cancers. The tumor specificity of FOLR1 makes it a promising therapeutic target for the treatment of cancer.

Product Specifications

Catalog Number C3038
Cell Line Name Human FOLR1-CHO-K1 Stable Cell Line
Gene Sequence P15328.3
Host Cell CHO-K1 (Adherent cells)
Quantity Two vials of frozen cells (~2x106 per vial)
Culture Medium DMEM with 10% FBS and 4 µg/ml puromycin
Freezing Medium 90% FBS and 10% DMSO
Storage Liquid nitrogen upon receipt
Product Datasheet: Download PDF

Representative Data

Detection of human FOLR1 expression on human FOLR1-CHO-K1 stable cells using a monoclonal antibody specific for human FOLR1 (BioLegend, Cat #908303)


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