| Catalog Number | Product | Size | Price | |
|---|---|---|---|---|
| C3038 | Human FOLR1-CHO-K1 Stable Cell Line | 2 vials | $4950 | Order |
| Catalog Number | C3038 |
|---|---|
| Cell Line Name | Human FOLR1-CHO-K1 Stable Cell Line |
| Accession Number | P15328.3 |
| Host Cell | Adherent CHO-K1 |
| Quantity | Two vials of frozen cells (2x106 per vial) |
| Culture Medium | DMEM with 10% FBS, 4 ug/ml puromycin |
| Freezing Medium | 90% FBS and 10% DMSO |
| Storage | Liquid nitrogen upon receipt |
| Product Datasheet: | Download PDF |
Detection of human FOLR1 expression on human FOLR1-CHO-K1 stable cells using a monoclonal antibody specific for human FOLR1 (BioLegend, Cat #908303)
Folate receptor 1 (Folate receptor alpha, FOLR1) is a glycosyl-phosphatidylinositol (GPI)-linked membrane-bound protein, which exhibits a high affinity for folic acid and its reduced folic acid derivatives. FOLR1 mediates delivery of 5-methyltetrahydrofolate to the interior of cells. FOLR1 is involved in several cellular processes, including cell growth, survival, and signaling pathways. FOLR1 is expressed in kidney, placenta, serum, milk, and in several cell lines, while its expression has been found to be elevated in tumors of epithelial origin compared to normal tissue, including ovarian, breast, brain, lung and colorectal cancers. The tumor specificity of FOLR1 makes it a promising therapeutic target for the treatment of cancer.
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